How Does the Gamma Knife Work?

By: Groshan Fabiola

The gamma knife is a state-of-the art medical device used to conduct highly precise, non-invasive brain surgeries. Gamma knife surgery dates back to 1967, when Swedish neurosurgeon, Lars Leksell, invented the gamma device. The gamma knife and the computerized treatment planning software that it employs allow physicians to locate and remove small tumors in the brain with extreme precision. During gamma knife surgery, multiple beams of radiation are simultaneously shot at the target area in the patient's brain without causing damage to surrounding healthy tissue.

How it Works
The gamma knife uses a technique called stereotactic radio surgery. About 200 beams of radiation converge three-dimensionally on a precise point in the brain, i.e. a tumor. This allows doctors to deliver intense doses of radiation to the target in a safe and efficient manner. The use of robotic technology allows the patient to be moved by precise, sub-millimeter increments during the procedure, ensuring that the radiation hits all parts of the targeted area.

Preparation
With the patient anesthetized, a rigid head frame that incorporates a 3D coordinate system surrounds the patient's skull. Imaging studies are then conducted on the patient's brain and the results are input into the gamma knife's computer system. A group of doctors then delineates the target areas and calculates the parameters of the gamma knife treatment. The best method for performing a treatment during a gamma knife session is by conducting several shots from different angles. A great deal of fine tuning and adjustments must be done in order to determine the optimal gamma knife positioning. When the final coordinates are determined, the head frame is attached to the gamma knife device so that the target area of the patient's brain will be at the exact center where the 200 or so precision radiation beams will intersect. Any given gamma knife surgery can take anywhere from a few minutes to a few hours to complete, depending on the kind of target being treated. The radiation "shots" are not felt by the patient, so there is no pain in that sense. Patients may return to normal activity fairly soon after gamma knife surgery. The gamma knife procedure is currently one of the most effective treatments for brain tumors. Acoustic neuroma gamma knife surgery is an especially effective treatment option, and is growing in popularity for treating acoustic neuroma.


About the Author
For more resources regarding gamma knife surgery or even about treatment for brain tumors and especially about acoustic neuroma gamma knife please review these pages.

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Gamma Knife robotic microradiosurgery of pituitary adenomas invading the cavernous sinus: treatment concept and results in 89 cases.


Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan, GKRmoto@aol.com.

Abstract

The objective of the present retrospective study was evaluation of results of "robotic microradiosurgery" of pituitary adenomas invading the cavernous sinus. Eighty-nine patients with such tumors underwent management using Leksell Gamma Knife model C with automatic positioning system. There were 77 residual and 12 recurrent neoplasms. The applied radiosurgical treatment plan was based on the use of multiple isocenters, mainly of smaller size, which were positioned compactly within the border of the lesion with resultant improved dose homogeneity, increased average dose within the target, and sharp dose fall outside the treated volume. The marginal dose varied from 12 to 25 Gy (mean, 18.2 Gy) in non-functional pituitary adenomas (43 cases), and from 12 to 35 Gy (mean, 25.2 Gy) in hormone-secreting ones (46 cases).

Vacancy for Staff Nurse at Newport Beach



Job Title:RN - Gamma Knife
Department:GAMMA KNIFE
Requisition Number:7649-11471
Job Category:Nursing
Interest:Staff Nurse
Shift:1st Shift
Status:Full-Time
Hours:8am - 6pm
Days:M-F
Qualifications:See job description

An Acoustic What? One patient's Acoustic Neuroma journey

An Acoustic What? One patient's Acoustic Neuroma journey Just how did an uncontroversial and mild mannered piano teacher become the first UK patient to cross the Atlantic to be treated by Dr Gil Lederman using Fractionated Stereotactic Radiosurgery? The journey began in 1995 when I was diagnosed with a benign brain tumour; an acoustic neuroma. At the time I was advised to have it removed surgically; a long and complicated procedure with serious side effects.

Archbold Gamma Knife treats 500th patient

THOMASVILLE — Abby Gibson used it for a malignant brain tumor.  Michelle Ughetto used it for an arteriovenous malformation.  In receiving their treatment, both represented two patients in a recent milestone reached by Archbold’s Gamma Knife Center.

 Seven years after offering Gamma Knife as a treatment option, Archbold’s Gamma Knife team has treated 500 patients, a milestone comprised of clinically and geographically diverse patients from across the Southeast.

 Gamma Knife treatment was first used in Stockholm, Sweden, in 1968 and has continuously evolved with advances in radiation physics, robotic controls and computerized treatment planning.  The treatment allows a team of physicians, a physicist and nurses to treat previously untreatable malignant and benign brain tumors, vascular malformations and functional disorders such as epilepsy, Parkinson’s disease and trigeminal neuralgia.

 With the precision of surgery without a scalpel or incision and lower risk, Gamma Knife’s 201 incredibly precise beams of gamma radiation differentiate it from other types of brain treatment.

KAROLINSKA UNIVERSITY HOSPITAL ACQUIRES LEKSELL GAMMA KNIFE PERFEXION TO EXPAND RADIOSURGERY VERSATILITY, EFFICIENCY IN BRAIN CANCER THERAPY

Prof. Lars Leksell (1907-1986), inventor of the radiosurgical instrument that bears his name and a faculty member of Karolinska University Hospital (Solna, Sweden), performed the world’s first Gamma Knife® surgery at nearby Sophiahemmet Hospital, the location of the first Leksell Gamma Knife. Karolinska University Hospital recently acquired Elekta’s fifth generation radiosurgery system, Leksell Gamma Knife® Perfexion™. Since January, Karolinska clinicians have been using the system to treat more patients per day and tumors that used to be hard to reach. Physicians also are much more easily treating multiple metastases in a single session.

While Karolinska clinicians are currently treating traditional Gamma Knife indications (metastases, meningiomas, arteriovenous malformations, dural fistulas, acoustic neuromas), the immediate impact Perfexion has made is the ease with which physicians can treat two or more metastases in one session.

“We treat five to ten metastases on a regular basis, because the automated collimator makes it possible to rapidly plan and treat multiple tumor isocenters,” Karolinska neurosurgeon Dr. Ernest Dodoo explains. “Suddenly, it is feasible to treat everything we see. Now, the question is not ‘Is it technically possible?’ but rather ‘Does it make sense clinically from a therapy standpoint?’”

Perfexion improves radiosurgery workflow

Leksell Gamma Knife Perfexion replaced two earlier generation Leksell Gamma Knife® 4C systems, one at Sophiahemmet Hospital and the other at Karolinska University Hospital. Each had been treating about 250 patients per year for the last three years. Since the late 1960s, Karolinska has used Gamma Knife surgery for approximately 10,000 patients, according Dr. Dodoo.

On January 11, Karolinska used Leksell Gamma Knife Perfexion to treat its first case, a patient with a glioblastoma. Since then, Karolinska has treated 120 patients with Perfexion and this single system already rivals the daily patient volume of the previous systems by virtue of its unique features. “We treated five patients in one day last week, including two quite complex cases,” he recalls. “With either of our previous systems that would have been logistically difficult. With Perfexion, up to five patients per day is absolutely realistic.”

In addition to the system’s automated collimator, the enhanced planning system for Leksell Gamma Knife Perfexion also is boosting the efficiency of Karolinska’s radiosurgery practice.

“Planning is a lot easier, more intuitive and very user friendly,” Dr. Dodoo notes. “We can visualize the isodose lines simultaneously as we trace them and the dynamic shaping makes dose planning much simpler. It really has changed our approach.”

The sophisticated automation that Perfexion brings to the clinic has transformed radiosurgery from a hands-on, technical procedure to one in which enhancing dose plans is the key objective, he adds. “Perfexion has allowed us to shift the focus from the technical, time-consuming part of treatment—changing collimators and adjusting table positions in half-millimeter steps—to creating the best dose plan for the patient.”

********

Editor’s note: Images and streaming video of Leksell Gamma Knife® Perfexion™ are available in Elekta’s Media Resources Center.


For further information, please contact:

Stina Thorman, Vice President Corporate Communications, Elekta AB

Tel: +46 8 587 254 37, email: stina.thorman@elekta.com

Time zone: CET: Central European

Michelle Lee, Director, Global Public Relations and Brand Management, Elekta

Tel: +1 770-670-2447, email: michelle.lee@elekta.com

Time zone: EDT: Eastern Daylight


******



About Elekta

Elekta is a human care company pioneering significant innovations and clinical solutions for treating cancer and brain disorders. The company develops sophisticated, state-of-the-art tools and treatment planning systems for radiation therapy and radiosurgery, as well as workflow enhancing software systems across the spectrum of cancer care.

Stretching the boundaries of science and technology, providing intelligent and resource-efficient solutions that offer confidence to both healthcare providers and patients, Elekta aims to improve, prolong and even save patient lives, making the future possible today.


Today, Elekta solutions in oncology and neurosurgery are used in over 5,000 hospitals globally, and every day more than 100,000 patients receive diagnosis, treatment or follow-up with the help of a solution from the Elekta Group.

Tumor control and hearing preservation after Gamma Knife radiosurgery for vestibular schwannomas in neurofibromatosis type 2.

Department of Neurosurgery and Gamma Knife, All India Institute of Medical Sciences, New Delhi, 110029, India, manishsinghsharma@gmail.com.

Abstract

To analyze the effect of Gamma Knife radiosurgery (GKS) on tumor control and hearing preservation rates in patients with vestibular schwannomas (VS) in a setting of neurofibromatosis type 2 (NF 2), a retrospective study was carried out at a tertiary-level referral Gamma Knife unit. Dose plans, pre- and postoperative radiology, and follow-up clinical records of patients with NF 2 who had undergone GKS for VS using a Leksell Gamma Knife (Elekta Instruments AB, Stockholm, Sweden) model B unit from 1997 to 2008 were reviewed.

Gamma Knife Surgery by Ganz Jeremy C

Read review of the book Gamma Knife Surgery by Ganz Jeremy C and buy the book online.
The book Gamma Knife Surgery by Ganz Jeremy C ISBN 0387824766 is available at Rs 1870, 32% discount and may qualify for free shipping anywhere in India. When you order the book Gamma Knife Surgery by Ganz Jeremy C at Indiaplaza.in, you are sure to receive a brand new copy and not an old copy or a used book.

Gamma Knife Centre in Singapore

Gamma Knife Centre
ParkwayHealth Day Surgery & Medical Centre
363 Balestier Road
Singapore 329784
Tel: (65) 8125 6109 / 6305 4453
Fax: (65) 6305 4454
Email: sgkc@gammaknife.com.sg 
Website : http://www.gammaknife.com.sg

Concerned husband - Lamictal side effects?

Hello Everyone. I'm new to this board after finding it through a google search. I've been reading through many posts but each addresses some part of the issue, so I thought I'd just ask my question and hope somebody out there might have some answers or at least some suggestions.

For background, my wife experienced a grand mal seizure just under 10 years ago which led to the detection of an AVM (artereovenous malformation) in the left parietal lobe of her brain. She had no seizure activity prior to this one, and it was brought on by over-exertion (she was training for a half marathon). Post-seizure, she was put on Dilantin (caused massive mood swings) and then switch to Nuerontin. She weaned herself off Neurontin as she felt "completely numb" when taking it, and her AVM was considered inoperable because of where it was in her brain.

Cobalt-60 source of radiation in West Delhi

New Delhi: (PTI) Experts today identified the material which led to a "very powerful" radiation in a West Delhi industrial area as Cobalt-60, the exposure to which left five persons injured including one seriously.


Scientists from the Bhaba Atomic Research Centre (BARC) and Narora Atomic Power Station also scanned Mayapuri Industrial area this morning to examine whether there was any other source of a similar emission in the vicinity.

Panic was triggered in the locality last night after the news of a radiation leak broke out with five persons falling ill after coming in contact with a "mysterious shining object" in a scrap shop.

Rocky Mountain Gamma Knife Centre

Address: 4231 W 16th Ave
City: Denver
County: Denver
State: Colorado
Zip Code: 80204-1335
Phone: 303-534-2662

About Gamma Knife

A gamma knife is a device used to treat brain tumors with a high dose of radiation therapy in one day. The device was invented at the Karolinska Institute in 1967 by Lars Leksell, a Swedish

Gamma Knife Surgery is a bloodless surgery for neurological diseases. The surgery does not require the skull to be opened for performance of the operation. The patient is treated in one session and can normally return home shortly after the surgery. It is a safe, precise, bloodless procedure.

Gamma Knife Radiosurgery can be useful for those patients who are not suitable for conventional open surgery due to illness or advanced age.

Yorkshire Medical Advance Marks First Anniversary By Treating Its 100th Patient

The Leeds Gamma Knife Centre, based in the £250m Bexley Wing at the city's St James's University Hospital has now treated its 100th patient with its hi-tech tool, a £3m gamma knife, which has revolutionised the treatment of a wide range of brain conditions, including cancers.

Yvonne Allen was first treated for a brain tumour in 2005, she had surgery through her skull in a five-hour operation, spent over a week in hospital including a spell in intensive care, and was not allowed to drive for six months.

After her annual MRI scan revealed a second tumour had started to grow, the former Leeds medical secretary became the 100th patient to be treated by Yorkshire's latest hi-tech tool in the fight against brain disease - a gamma knife.

Less than 24 hours after arriving at the Leeds Gamma Knife Centre for the 60-minute procedure, 68-year-old Yvonne was back at her home in South Cliff, Scarborough - even stopping off en route for some shopping!

The £3m gamma knife revolutionises the treatment of a wide range of brain conditions, including cancers. Doctors use 192 beams of gamma radiation to target and destroy abnormalities with pinpoint accuracy, avoiding the need for complex open surgery.

The Leeds Gamma Knife Centre, based in the £250m Bexley Wing at the city's St James's University Hospital, has treated both NHS and private patients from across Great Britain and Ireland since it first opened a year ago. Waiting times are minimal and many are treated as outpatients, well enough to go home the same day as the procedure.

The equipment in Leeds is manufactured by Elekta and is known as the Perfexion - the most advanced system in the world - and is one of only four gamma knives operating across the whole of the UK.

"We are determined to put Leeds at the forefront of gamma knife technology in the UK," said Kerry Jackson, Chief Executive of Nova Healthcare which runs the service in partnership with the hospital. "To mark our first anniversary by treating our 100th patient is an important milestone for us.

"Gamma knife technology adds an extra dimension to the treatment options for people with a range of malignant and benign brain diseases and we are delighted to bring it to West Yorkshire for the very first time."

Yvonne was first diagnosed as suffering from a benign meningioma - a tumour that affects the linings of the brain - when she retired to Scarborough after spending her working life as a secretary and receptionist in health centres at Shadwell and Burmantofts in Leeds.

Her balance had become unsteady and she suffered an increasing number of falls. A scan in 2005 revealed a 2cm tumour pressing against the lining of her brain and she underwent major surgery to remove as much of it as possible.

Doctors monitored her condition through regular scans as there was another tumour at the back of her eye and her most recent check-up revealed Yvonne's worst fear - that tumour had almost doubled in size.

Before undergoing the hi-tech procedure, Yvonne was placed in a lightweight head frame to prevent her head from moving during treatment, ensuring the gamma rays are targeted at precisely the right area, and surrounding healthy tissue is protected.

She laid on the gamma knife while Leeds neurosurgeon Mr Stuart Ross worked with radiographers in an adjoining room, speaking to her throughout. Patients are even encouraged to bring their own music in with them.

Yvonne, who is married to Mike, and has a daughter, Dawn, and one grandson, Alexander, said: "Had I lived closer, I could have gone home that same day but instead chose to stay overnight at the hospital's own hotel.

"I went home to Scarborough the next morning - and felt well enough to stop for a spot of shopping on the way home, buying some new shoes!

"The whole experience was so completely different to the major surgery I had to remove my first tumour. The gamma knife is a fantastic machine, offering new hope and new treatment options for so many patients.

"I am just so pleased that I have been part of its first year of success."

For further information please call Richard Chew, Different PR, on 0845 389 2626

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PDF Version - Optimization of Gamma Knife Radiosurgery

The Gamma Knife is a highly specialized treatment unit that pro- .... The ideal optimization technique for Gamma Knife treatment planning must be ...

YORKSHIRE MEDICAL ADVANCE MARKS FIRST ANNIVERSARY BY TREATING ITS 100th PATIENT

The Leeds Gamma Knife Centre, based in the £250m Bexley Wing at the citys St Jamess University Hospital has now treated its 100th patient with its hi-tech tool, a £3m gamma knife, which has revolutionised the treatment of a wide range of brain conditions, including cancers.

WHEN Yvonne Allen was first treated for a brain tumour in 2005, she had surgery through her skull in a five-hour operation, spent over a week in hospital including a spell in intensive care, and was not allowed to drive for six months.

After her annual MRI scan revealed a second tumour had started to grow, the former Leeds medical secretary became the 100th patient to be treated by Yorkshires latest hi-tech tool in the fight against brain disease a gamma knife.

Less than 24 hours after arriving at the Leeds Gamma Knife Centre for the 60-minute procedure, 68-year-old Yvonne was back at her home in South Cliff, Scarborough even stopping off en route for some shopping!

The £3m gamma knife revolutionises the treatment of a wide range of brain conditions, including cancers. Doctors use 192 beams of gamma radiation to target and destroy abnormalities with pinpoint accuracy, avoiding the need for complex open surgery.

The Leeds Gamma Knife Centre, based in the £250m Bexley Wing at the citys St Jamess University Hospital, has treated both NHS and private patients from across Great Britain and Ireland since it first opened a year ago. Waiting times are minimal and many are treated as outpatients, well enough to go home the same day as the procedure.

The equipment in Leeds is manufactured by Elekta and is known as the Perfexion - the most advanced system in the world - and is one of only four gamma knives operating across the whole of the UK.

We are determined to put Leeds at the forefront of gamma knife technology in the UK, said Kerry Jackson, Chief Executive of Nova Healthcare which runs the service in partnership with the hospital. To mark our first anniversary by treating our 100th patient is an important milestone for us.

Gamma knife technology adds an extra dimension to the treatment options for people with a range of malignant and benign brain diseases and we are delighted to bring it to West Yorkshire for the very first time.

Yvonne was first diagnosed as suffering from a benign meningioma a tumour that affects the linings of the brain when she retired to Scarborough after spending her working life as a secretary and receptionist in health centres at Shadwell and Burmantofts in Leeds.

Her balance had become unsteady and she suffered an increasing number of falls. A scan in 2005 revealed a 2cm tumour pressing against the lining of her brain and she underwent major surgery to remove as much of it as possible.

Doctors monitored her condition through regular scans as there was another tumour at the back of her eye and her most recent check-up revealed Yvonnes worst fear that tumour had almost doubled in size.

Before undergoing the hi-tech procedure, Yvonne was placed in a lightweight head frame to prevent her head from moving during treatment, ensuring the gamma rays are targeted at precisely the right area, and surrounding healthy tissue is protected.

She laid on the gamma knife while Leeds neurosurgeon Mr Stuart Ross worked with radiographers in an adjoining room, speaking to her throughout. Patients are even encouraged to bring their own music in with them.

Yvonne, who is married to Mike, and has a daughter, Dawn, and one grandson, Alexander, said: Had I lived closer, I could have gone home that same day but instead chose to stay overnight at the hospitals own hotel.

I went home to Scarborough the next morning and felt well enough to stop for a spot of shopping on the way home, buying some new shoes!

The whole experience was so completely different to the major surgery I had to remove my first tumour. The gamma knife is a fantastic machine, offering new hope and new treatment options for so many patients.

I am just so pleased that I have been part of its first year of success.

ENDS

For further information please call Richard Chew, Different PR, on 0845 389 2626

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Name: Richard Chew
Website: http://www.novahealthcare.co.uk/gammaknife.php
Email: richard@differentpr.co.uk
Phone: 0845 389 2626
Address: Pannal Business Park, Station Road, Harrogate, North Yorkshire, HG
City: Harrogate
County/State: North Yorkshire
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Country: United Kingdom

Brain Tumor Treatment and Gamma Knife Radiosurgery

Gamma Knife Radiosurgery For Essential Tremor: A Case Report And Review Of The Literature

http://www.docguide.com/news/content.nsf/cases/79A61EFCF316DC06852576EE0068133E?OpenDocument&id=48dde4a73e09a969852568880078c249&c=Geriatrics&count=10

Gamma knife treatment for refractory cluster headache: prospective open trial

Gamma knife treatment for refractory cluster headache: prospective open trial
  • A Donnet,
  • D Valade,
  • J RĂ©gis
J Neurol Neurosurg Psychiatry 2005;76:218-221 doi:10.1136/jnnp.2004.041202

Postgraduate Institute of Medical Education & Research

Sector 12
Chandigarh-160012, India

NIMHANS

Department of Neurosurgery
Hosur Road
Bangalore - 560029, India

All India Institute of Medical Sciences


Ansari Nagar,
New Delhi-110029

Hinduja Hospital and Medical Research Centre,

Veer Savarkar Marg,
Mahim, Mumbai-400 016
India.

Ojjus Medicare Goodwill Hospital

D-141 A&B
Sec-40, Noida-201303
UP, India. 







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Rancan Gamma Knife Centre

VIMHANS Hospital Campus
1, Institutional Area
Nehru Nagar,
New Delhi-110065


Neurospinal & Medical Institute

100/1, Depot Line,
Mans Field Street, Saddar
Karanchi-74400
Pakistan
Tel : 2259959, 2258848, 2256307
Fax : 2230310
Email : neurospi@cyber.net.pk

Gamma Knife Stereotactic Radiosurgery

Piedmont Hospital installed the fourth Gamma knife unit in North America over 20 years ago and has had continuous experience in the use of this device ever since.

Gamma Knife Surgery is a minimally invasive procedure that treats tumors and vascular abnormalities within the brain with intersecting beams of radiation therapy, eliminating the need for traditional open neurosurgery. This procedure is commonly used to treat brain tumors, arteriovenous malformations, acoustic neuromas/schwannomas, trigeminal neuralgia and other abnormalities within the brain.

Read more

Epilepsy Alternative Treatment: Gamma Knife, EEG Neurofeedback

There are several different alternative treatment strategies for individuals that have epilepsy. Doctors commonly prescribe medications in order to cope with the symptoms associated with epilepsy, such as the seizures that naturally ...

Good Samaritan Medical Center offers new gamma knife technology

WEST PALM BEACH — Good Samaritan Medical Center has upgraded its brain surgery procedures with the addition of the latest technology, the Leksell Gamma Knife® PERFEXION™. This cutting-edge, $4 million system will completely replace the previous Gamma Knife unit, and expands the range of treatment options and comfort level for patients.

If you have any query regarding Gamma Knife Radiosurgery you can contact us

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