Study Shows Gamma Knife Radiosurgery For Patients With Multiple Brain Metastases Is Best For Sparing Healthy Tissue

The volume of normal brain tissue exposed to radiation during treatment for multiple metastases appears to depend on which stereotactic radiosurgery system is employed, according to a recent study in the Journal of Neurosurgery(1). Comparing treatment plans developed for use by three different treatment systems for a single patient (already previously treated with Leksell Gamma Knife®), researchers found that Gamma Knife plans would result in "much smaller normal brain volumes receiving any particular dose" than the two other systems' plans.

The study compared treatment plans by Washington Fremont Hospital's (Fremont, Calif.) Leksell Gamma Knife® Perfexion™, the University of Utah's (Salt Lake City) BrainLAB Novalis™ system and the University of California San Francisco's Accuray CyberKnife® system and involved a patient with 12 metastatic brain lesions. Gamma Knife is widely regarded as the gold standard for treating brain metastases.

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